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In light of these findings, we postulated that long-term fluctuating glycemia, especially after extra carbohydrate intake, continuously and waveringly generates extra ROS, which in turn damages the pancreatic -cells

Downregulation of IL-6, TLR4, PTGS2, and IL-1 expression were also a consequence of BBR treatment [56]

PMCID: PMC6523540

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